EnerGex Syringe 60g - Horse Energy Supplement
- Fast and safe source of energy
- For use before, during, and after exercise
- Maintains glucose levels and helps restore glycogen levels
- For sustained performance
- Convenient on-the-go syringe is easy to administer and transport
EnerGex is a safer source of carbohydrate (energy) compared with simple sugars, which can lead to adverse effects on behavior and performance. It is low-glycemic, meaning it leads to a slower rate of glucose entry into the blood, avoiding high peaks and sudden drops in blood glucose levels, and induces lower insulin responses. This leads to a more balanced and prolonged energy supply. In one study, Energex was shown to lead to lower peak in glucose, longer to reach peak in glucose, and lower insulin responses at each time point measured following administration of either Energex or equal amounts of sucrose. In another study, even though Energex once again induced a lower glucose and insulin response after administering either Energex or sucrose, Energex was still able to effectively restore muscle glycogen levels following exercise.
Glucose is the most important energy source for horses during exercise. Low blood glucose levels are associated with fatigue and reduced performance, and maintaining blood glucose levels is especially important during prolonged exercise, when competing, and for horses that are lacking in energy. EnerGex provides a means of increasing blood glucose levels in a controlled, safe, and sustainable way, and EnerGex can also be given after training or competition to aid recovery. Further, EnerGex helps restore muscle glycogen levels, and exercise performance in horses is almost always limited by muscle glycogen concentration. Glycogen is formed from simple sugars linked together and is the animal equivalent of starch in plants. Recovery in muscle glycogen after exercise is reduced if there is insufficient dietary intake of carbohydrate (sugars) to meet the horse’s needs - either from high athletic performance or simply because of reduced appetite. By increasing the available energy supply, EnerGex can help deliver more prolonged and consistent performance results. EnerGex also supports improved fat oxidation during physical activity, as high levels of glucose and/or insulin hinder the use of lipids (fat) as an energy source. By increasing the utilization of fat during exercise, EnerGex thus helps enhance endurance performance that relies on fat metabolism.
EnerGex is ideal for use before, during, and following exercise to support energy delivery. Given by a convenient syringe, EnerGex is portable enough to take on the trails or to the show ring as a boost mid-ride. It can also be used as an energy booster in lethargic horses and to maintain blood glucose levels in situations where food intake is decreased, such as during travelling or when appetite is reduced. EnerGex is given by mouth as a paste and is rapidly absorbed, increasing blood glucose levels within 30 minutes and can maintain an increased level for 2 hours.
Instructions for Use and Feeding Guide:
Pony - approximately 550lbs ½ syringe
Horse - approximately 1100lbs 1 syringe
Large Horse - over 1650lbs 1 syringe
-EnerGex can be given before, during, or after competition or training.
-If given before the start of exercise, EnerGex should be given within 15 minutes prior to the start.
-For intense exercise, 2 syringes may be given. Additional syringes may be given every 1-2 hours.
-Given immediately after exercise, EnerGex promotes recovery.
Ingredients & Composition:
One of our core values is transparency. That’s why we list all the active ingredients per daily feeding rate so you know exactly what your horse is getting.
Per 60g EnerGex Syringe delivers: 40g of slow release, complex carbohydrate.
Crude Protein <1%; Crude Fiber <1%; Crude Oils & Fats 15%; Crude Ash 43%; Sodium 2%; Moisture 10.2%.
Additives (per kg):
Technological Additives: Xanthan gum (E415) 5g; Potassium Sorbate (E202) 1g; Sodium Benzoate (1k301) 1g.
Research (glucose/insulin response):
QUESTION: Do blood glucose and insulin responses to high and low glycemic index carbohydrate supplements differ?
- Foods with a high glycemic index (GI), such as those containing high amounts of dietary starch, release sugar rapidly whereas low GI foods release energy more slowly.
Aim of Study
To determine the blood glucose and insulin responses to administration of a low GI, slow release carbohydrate supplement (EnerGex, Science Supplements) compared with an equivalent energy load of high GI carbohydrate (sugar).
Double-blind = none of the clinicians or data analysts knew which supplement any given horses received on each test days. Blinding reduces bias caused by people wanting to see a positive effect with the treatment under investigation.
Crossover trial = all horses received both low and high GI carbohydrates allowing the response of a horse to low GI carbohydrate to be compared with the same horse's response to high GI carbohydrate. Removing horse to horse variation in this way makes crossover trials potentially more efficient than similar sized, parallel group trials in which each horse is exposed to only one treatment.
Washout = the time between treatments (low/high GI carbohydrate). A washout period of time allows the treatment from the first period to be washed out of the patient's system.
Six clinically healthy horses were randomly allocated to receive a one-off dose of 1g per kg body weight of either sucrose (sugar) or EnerGex. These carbohydrate supplements were dissolved in 4 litres of water and given by stomach tube. Serial blood samples were taken before and at 0, 30, 45, 60, 90, 120, 180, and 480 minutes following administration of carbohydrate for later glucose and insulin measurement. After a 48 h washout period, all horses then received the other carbohydrate solution and blood sampling as previously described.
- Blood glucose (Fig. 1) and insulin (Fig. 2) concentrations increased more slowly with EnerGex compared to sucrose.
- Glucose concentration at 45 min was significantly lower with EnerGex compared with sucrose. Blood glucose concentration peaked later (90-120 min) with EnerGex compared to sucrose (60 min) (Fig. 1).
- While peak plasma insulin concentration showed a plateau around 45-60 min and a peak around 120 min with both EnerGex and sucrose, plamsa insulin was significantly lower with Energex at every time point (Fig. 2).
Take Home Message
- The low GI carbohydrate supplement EnerGex results in a more controlled and sustained rise in blood glucose than an equivalent load of sugar provided as sucrose.
- EnerGex induces considerably less metabolic disturbance as shown by a 50% lower insulin response. This response makes EnerGex suitable for use in horses during or following exercise, in cases where hindgut function is compromised, in horses with depressed appetite as a result of illness or stress (e.g. transport, stabling away at competitions) and as an adjunct or alternative to parenteral nutrition of feeding via nasogastric intubation.
Research (glucose/insulin response and glycogen impact):
QUESTION: Can a low glycemic carbohydrate restore muscle glycogen as well as simple sugar?
- Glycogen is a carbohydrate stored in muscles for use as an energy source during exercise.
- Foods with a high glycemic index (GI), such as sucrose, can be used to replace muscle glycogen after exercise.
- High GI foods also induce higher insulin responses than lower GI foods.
- High insulin levels are associated with long-term development of insulin resistance and short-term suppression of fat utilization.
- Feeds that can restore glycogen without inducing high insulin levels are of interest.
Aim of Study
To investigate if a low GI carbohydrate solution (slower energy release) can restore muscle glycogen post-exercise as well as a high GI solution (sucrose).
Blinded = researchers did not know which carbohydrate solution horses received.
Randomized = which horses were given placebo was pre-determined by a random system rather than a person deciding at the time of seeing a horse. This removes bias in the results caused by selecting only certain horses (e.g. less lame horses) to have a particular treatment.
Muscle glycogen replacement was studied in 11 horses which underwent treadmill exercise to deplete muscle glycogen followed by a carbohydrate replacement treatment. Treadmill exercise consisted of 15 min at a heart rate of 130-140 bpm with a treadmill incline of 6-10°, 15 min at a slope of 6-10° and heart rate between 150-180 bpm, and then 5 min at a slope of 0-10° with a heart rate between 180-200 bpm. Horses were rested for 30 min and then performed six 1 min sprints at a slope of 4-10° with a target heart rate of 200-220 bpm, with 5 min walking at the same slope between sprints. Thirty minutes after exercise horses were randomly allocated to receive either a low glycemic index or high glycemic index carbohydrate solution by stomach tube. The low glycemic index carbohydrate supplement consisted of 1.3 g/kg EnerGex (Science Supplements). The high glycemic index carbohydrate supplement was given as an equivalent calorie, same volume solution of sucrose. Muscle biopsies were taken from the middle gluteal muscle, at a depth of 8 cm, in each horse before exercise, immediately post-exercise, and at 24 h following treatment. Blood samples for glucose and insulin analysis were taken before, and at 0, 15, 30, 45, 60, 90, 120, 150, 180, 210, 240, and 1440 min after supplementation.
- There was no significant difference in pre-exercising blood glucose concentrations in horses administered sucrose or EnerGex (Fig. 1) indicating that any changes during the trial were due to the carbohydrates given.
Figure 1: Blood glucose concentration post-exercise following nasogastric administration of EnerGex™ or sucrose.
- Sucrose caused a significantly higher insulin response than EnerGex (Fig. 2). Blood glucose and insulin were both elevated for significantly longer in horses treated with sucrose versus EnerGex.
Figure 2: Blood insulin concentration post-exercise following nasogastric administration of EnerGex™ or sucrose. Timepoints with different letters denotes significantly different mean blood insulin concentration (P<0.05) between sucrose and EnerGex supplemented horses.
- Muscle glycogen replacement was similar for both carbohydrate supplements (Fig. 3). At 24h following exercise, muscle glycogen recovery was 63% with EnerGex compared to 58% with sucrose.
Figure 3: Effect of EnerGex™ and sucrose supplementation on mean (±SEM) muscle glycogen concentration before (pre-exercise), 0 h (post-exercise but prior to supplementation) and 24 h (24 h post-exercise). dw= dry weight.
Take Home Messages
- The low GI carbohydrate (EnerGex) replaced the same amount of muscle glycogen as the high GI solution (sucrose) within 24 h of intense treadmill exercise.
- Administration of sucrose to horses resulted in higher blood glucose levels, which stimulated an increased insulin response. In contrast, EnerGex supplementation elicited a significantly lower insulin response, possibly due to a slower, steadier glucose digestion and absorption in the small intestine.
- EnerGex given before and during aerobic exercise may preserve glycogen stores for a longer duration of time, thus delaying time to fatigue. Additionally, due to the lower blood insulin response to EnerGex, there is a greater potential for the body to utilize fatty acid oxidation during exercise, thus sparing muscle glycogen.